Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis

In amyotrophic lateral sclerosis (ALS), an adult onset disease in which there is progressive degeneration of motoneurones, it has been suggested that an intrinsic hyperexcitability of motoneurones (i.e. an increase in their firing rates), contributes to excitotoxicity and to disease onset. Here we s...

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Detaylı Bibliyografya
Asıl Yazarlar: Delestrée, Nicolas, Manuel, Marin, Iglesias, Caroline, Elbasiouny, Sherif M, Heckman, C J, Zytnicki, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell publishing Ltd 2014
Konular:
Neuroscience: Neurobiology of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979619/
https://ncbi.nlm.nih.gov/pubmed/24445319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.265843
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