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A Modified Model of T-Cell Differentiation Based on mTOR Activity and Metabolism
Current models of T-helper-cell differentiation depict the generation of effector cells from a naïve T cell based on the cytokine environment upon T-cell-receptor engagement. We propose a new model of CD4(+) T-cell activation, differentiation, and function whereby the outcome of antigen recognition...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979500/ https://ncbi.nlm.nih.gov/pubmed/24100582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2013.78.020214 |
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