Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks

WW domains are small modules present in regulatory and signaling proteins that mediate specific protein-protein interactions. The WW domain-containing oxidoreductase (WWOX) encodes a 46-kDa tumor suppressor that contains two N-terminal WW domains and a central short-chain dehydrogenase/reductase dom...

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Bibliographic Details
Main Authors: Abu-Odeh, Mohammad, Bar-Mag, Tomer, Huang, Haiming, Kim, TaeHyung, Salah, Zaidoun, Abdeen, Suhaib K., Sudol, Marius, Reichmann, Dana, Sidhu, Sachdev, Kim, Philip M., Aqeilan, Rami I.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979411/
https://ncbi.nlm.nih.gov/pubmed/24550385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.506790
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