Death Domain-associated Protein 6 (Daxx) Selectively Represses IL-6 Transcription through Histone Deacetylase 1 (HDAC1)-mediated Histone Deacetylation in Macrophages

As a multifunctional nuclear protein, death domain-associated protein 6 (Daxx) regulates a wide range of biological processes, including cell apoptosis and gene transcription. However, the function of Daxx in innate immunity remains unclear. In our study, we show that Daxx is highly expressed in mac...

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Autori principali: Yao, Zhenyu, Zhang, Qian, Li, Xia, Zhao, Dezhi, Liu, Yiqi, Zhao, Kai, Liu, Yin, Wang, Chunmei, Jiang, Minghong, Li, Nan, Cao, Xuetao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979371/
https://ncbi.nlm.nih.gov/pubmed/24550390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533992
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