Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity

Histone deacetylase 6 (HDAC6), a class IIb HDAC, plays an important role in many biological and pathological processes. Previously, we found that ERK1, a downstream kinase in the mitogen-activated protein kinase signaling pathway, phosphorylates HDAC6, thereby increasing HDAC6-mediated deacetylation...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Jheng-Yu, Xiang, Shengyan, Zhang, Mu, Fang, Bin, Huang, He, Kwon, Oh Kwang, Zhao, Yingming, Yang, Zhe, Bai, Wenlong, Bepler, Gerold, Zhang, Xiaohong Mary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808760/
https://ncbi.nlm.nih.gov/pubmed/29259132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.795955
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