Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

Epigenetic modifiers have fundamental roles in defining unique cellular identity through the establishment and maintenance of lineage-specific chromatin and methylation status(1). Several DNA modifications such as 5-hydroxymethylcytosine (5hmC) are catalysed by the ten eleven translocation (Tet) met...

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Pubblicato in:Nature
Autori principali: Zhang, Qian, Zhao, Kai, Shen, Qicong, Han, Yanmei, Gu, Yan, Li, Xia, Zhao, Dezhi, Liu, Yiqi, Wang, Chunmei, Zhang, Xiang, Su, Xiaoping, Liu, Juan, Ge, Wei, Levine, Ross L., Li, Nan, Cao, Xuetao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697747/
https://ncbi.nlm.nih.gov/pubmed/26287468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15252
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