DNA Damage-Binding Complex Recruits HDAC1 to Repress Bcl-2 Transcription in Human Ovarian Cancer Cells

Elevated expression of the anti-apoptotic factor Bcl-2 is believed to be one of the contributing factors to an increased relapse rate associated with multiple cisplatin-resistant cancers. DNA damage-binding protein complex subunit 2 (DDB2) has recently been revealed to play an important role in sens...

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Hauptverfasser: Zhao, Ran, Han, Chunhua, Eisenhauer, Eric, Kroger, John, Zhao, Weiqiang, Yu, Jianhua, Selvendiran, Karuppaiyah, Liu, Xingluo, Wani, Altaf A., Wang, Qi-En
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962721/
https://ncbi.nlm.nih.gov/pubmed/24249678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0281
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