Histone Deacetylase 6 (HDAC6) Deacetylates Survivin for Its Nuclear Export in Breast Cancer

Survivin is an oncogenic protein that is highly expressed in breast cancer and has a dual function that is dependent on its subcellular localization. In the cytosol, survivin blocks programmed cell death by inactivating caspase proteins; however, in the nucleus it facilitates cell division by regula...

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Bibliografiset tiedot
Päätekijät: Riolo, Matthew T., Cooper, Zachary A., Holloway, Michael P., Cheng, Yan, Bianchi, Cesario, Yakirevich, Evgeny, Ma, Li, Chin, Y. Eugene, Altura, Rachel A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322878/
https://ncbi.nlm.nih.gov/pubmed/22334690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308791
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