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Inherent Instability of the Retinitis Pigmentosa P23H Mutant Opsin

The P23H opsin mutation is the most common cause of autosomal dominant retinitis pigmentosa. Even though the pathobiology of the resulting retinal degeneration has been characterized in several animal models, its complex molecular mechanism is not well understood. Here, we expressed P23H bovine rod...

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書誌詳細
主要な著者: Chen, Yuanyuan, Jastrzebska, Beata, Cao, Pengxiu, Zhang, Jianye, Wang, Benlian, Sun, Wenyu, Yuan, Yiyuan, Feng, Zhaoyang, Palczewski, Krzysztof
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979360/
https://ncbi.nlm.nih.gov/pubmed/24515108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551713
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