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Myeloid-Specific IκB Kinase β Deficiency Decreases Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

OBJECTIVE: Inflammatory responses are the driving force of atherosclerosis development. IκB kinase β (IKKβ), a central coordinator in inflammation through regulation of nuclear factor-κB, has been implicated in the pathogenesis of atherosclerosis. Macrophages play an essential role in the initiation...

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Hlavní autoři: Park, Se-Hyung, Sui, Yipeng, Gizard, Florence, Xu, Jinxian, Rios-Pilier, Jennifer, Helsley, Robert N., Han, Seong-Su, Zhou, Changcheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979309/
https://ncbi.nlm.nih.gov/pubmed/23023371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.254573
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