Srs2 prevents Rad51 filament formation by repetitive scrunching of DNA

Srs2 dismantles presynaptic Rad51 filaments and prevents its re-formation as an anti-recombinase. However, the molecular mechanism by which Srs2 accomplishes these tasks remains unclear. Here we report a single molecule fluorescence study of the dynamics of Rad51 filament formation and its disruptio...

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Bibliographic Details
Main Authors: Qiu, Yupeng, Antony, Edwin, Doganay, Sultan, Ran Koh, Hye, Lohman, Timothy, Myong, Sua
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979297/
https://ncbi.nlm.nih.gov/pubmed/23939144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3281
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