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Srs2 prevents Rad51 filament formation by repetitive scrunching of DNA

Srs2 dismantles presynaptic Rad51 filaments and prevents its re-formation as an anti-recombinase. However, the molecular mechanism by which Srs2 accomplishes these tasks remains unclear. Here we report a single molecule fluorescence study of the dynamics of Rad51 filament formation and its disruptio...

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Detalhes bibliográficos
Main Authors: Qiu, Yupeng, Antony, Edwin, Doganay, Sultan, Ran Koh, Hye, Lohman, Timothy, Myong, Sua
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979297/
https://ncbi.nlm.nih.gov/pubmed/23939144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3281
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