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Crystal structure of Na(v)AP, an orthologue of the NaChBac voltage-gated sodium channel
Voltage-gated sodium (Na(v)) channels are essential for the rapid depolarization of nerve and muscle(1), and are important drug targets(2). A family of bacterial Na(v) channels, exemplified by NaChBac (Na(+)-selective Channel of Bacteria)(3), provides a good model system for structure-function analy...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979295/ https://ncbi.nlm.nih.gov/pubmed/22678295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11054 |
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