Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na(+) channels in nanodisc

NaChBac, the first bacterial voltage-gated Na(+) (Na(v)) channel to be characterized, has been the prokaryotic prototype for studying the structure–function relationship of Na(v) channels. Discovered nearly two decades ago, the structure of NaChBac has not been determined. Here we present the single...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gao, Shuai, Valinsky, William C., On, Nguyen Cam, Houlihan, Patrick R., Qu, Qian, Liu, Lei, Pan, Xiaojing, Clapham, David E., Yan, Nieng
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322032/
https://ncbi.nlm.nih.gov/pubmed/32513729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922903117
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