Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na(+) channels in nanodisc

NaChBac, the first bacterial voltage-gated Na(+) (Na(v)) channel to be characterized, has been the prokaryotic prototype for studying the structure–function relationship of Na(v) channels. Discovered nearly two decades ago, the structure of NaChBac has not been determined. Here we present the single...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gao, Shuai, Valinsky, William C., On, Nguyen Cam, Houlihan, Patrick R., Qu, Qian, Liu, Lei, Pan, Xiaojing, Clapham, David E., Yan, Nieng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322032/
https://ncbi.nlm.nih.gov/pubmed/32513729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922903117
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