Crystal structure of Na(v)AP, an orthologue of the NaChBac voltage-gated sodium channel

Voltage-gated sodium (Na(v)) channels are essential for the rapid depolarization of nerve and muscle(1), and are important drug targets(2). A family of bacterial Na(v) channels, exemplified by NaChBac (Na(+)-selective Channel of Bacteria)(3), provides a good model system for structure-function analy...

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Hlavní autoři: Zhang, Xu, Ren, Wenlin, DeCaen, Paul, Yan, Chuangye, Tao, Xiao, Tang, Lin, Wang, Jingjing, Hasegawa, Kazuya, Kumasaka, Takashi, He, Jianhua, Wang, Jiawei, Clapham, David E., Yan, Nieng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979295/
https://ncbi.nlm.nih.gov/pubmed/22678295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11054
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