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Sca1-positive murine pituitary adenoma cells show tumor growth advantage

The role of tumor stem cells in benign tumors such as pituitary adenomas remains unclear. We investigated whether cells within pituitary adenomas that spontaneously develop in Rb+/− mice are hierarchically distributed with a subset being responsible for tumor growth. Cells derived directly from such...

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Detalhes bibliográficos
Main Authors: Donangelo, Ines, Ren, Song-Guang, Eigler, Tamar, Svendsen, Clive, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978815/
https://ncbi.nlm.nih.gov/pubmed/24481638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0229
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