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T-cell Engager-armed Oncolytic Vaccinia Virus Significantly Enhances Antitumor Therapy
Oncolytic vaccinia virus (VV) therapy has shown promise in preclinical models and in clinical studies. However, complete responses have rarely been observed. This lack of efficacy is most likely due to suboptimal virus spread through the tumor resulting in limited tumor cell destruction. We reasoned...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978793/ https://ncbi.nlm.nih.gov/pubmed/24135899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.240 |
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