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T-cell Engager-armed Oncolytic Vaccinia Virus Significantly Enhances Antitumor Therapy
Oncolytic vaccinia virus (VV) therapy has shown promise in preclinical models and in clinical studies. However, complete responses have rarely been observed. This lack of efficacy is most likely due to suboptimal virus spread through the tumor resulting in limited tumor cell destruction. We reasoned...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978793/ https://ncbi.nlm.nih.gov/pubmed/24135899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.240 |
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