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NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis
INTRODUCTION: MicroRNAs (miRNAs) down-regulate their target genes. The intronic miR-140, present in the WW domain containing E3 ubiquitin protein ligase 2 (WWP2) gene, decreases the expression of genes that play detrimental roles in osteoarthritis (OA). As the expression level of miR-140 is signific...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978709/ https://ncbi.nlm.nih.gov/pubmed/24257415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4387 |
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