Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo

BACKGROUND: Ephrins and their related receptors have been implicated in some developmental events. We have demonstrated that ephrin-B2 (EFNB2) could play a role in knee joint pathology associated with osteoarthritis (OA). Here, we delineate the in vivo role of EFNB2 in musculoskeletal growth, develo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Valverde-Franco, Gladys, Lussier, Bertrand, Hum, David, Wu, Jiangping, Hamadjida, Adjia, Dancause, Numa, Fahmi, Hassan, Kapoor, Mohit, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791873/
https://ncbi.nlm.nih.gov/pubmed/26980243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0965-6
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