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An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

INTRODUCTION: Despite many advances in our understanding of the molecular basis of disc degeneration, there remains a paucity of preclinical models which can be used to study the biochemical and molecular events that drive disc degeneration, and the effects of potential therapeutic interventions. Th...

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Bibliographic Details
Main Authors: Markova, Dessislava Z, Kepler, Christopher K, Addya, Sankar, Murray, Hallie B, Vaccaro, Alexander R, Shapiro, Irving M, Greg Anderson, D, Albert, Todd J, Risbud, Makarand V
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978582/
https://ncbi.nlm.nih.gov/pubmed/24171898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4301
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