miR-31 controls osteoclast formation and bone resorption by targeting RhoA

INTRODUCTION: Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppr...

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Bibliografiske detaljer
Main Authors: Mizoguchi, Fumitaka, Murakami, Yousuke, Saito, Tetsuya, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978447/
https://ncbi.nlm.nih.gov/pubmed/24004633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4282
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