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Concurrent Suppression of Integrin α5, Radixin, and RhoA Phenocopies the Effects of miR-31 on Metastasis

miR-31 inhibits breast cancer metastasis via the pleiotropic suppression of a cohort of pro-metastatic target genes that include integrin α5, radixin, and RhoA. We previously demonstrated that the concomitant overexpression of integrin α5, radixin, and RhoA was capable of overriding the anti-metasta...

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Bibliographic Details
Main Authors: Valastyan, Scott, Chang, Amelia, Benaich, Nathan, Reinhardt, Ferenc, Weinberg, Robert A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891350/
https://ncbi.nlm.nih.gov/pubmed/20530680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0410
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