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Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis
It remains unclear whether a microRNA (miRNA) affects a given phenotype via concomitant down-regulation of its entire repertoire of targets or instead by suppression of only a modest subset of effectors. We demonstrate that inhibition of breast cancer metastasis by miR-31—a miRNA predicted to modula...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779763/ https://ncbi.nlm.nih.gov/pubmed/19875476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1832709 |
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