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miR-31 controls osteoclast formation and bone resorption by targeting RhoA

INTRODUCTION: Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppr...

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Detalhes bibliográficos
Main Authors: Mizoguchi, Fumitaka, Murakami, Yousuke, Saito, Tetsuya, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978447/
https://ncbi.nlm.nih.gov/pubmed/24004633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4282
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