miR-31 controls osteoclast formation and bone resorption by targeting RhoA

INTRODUCTION: Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppr...

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Dades bibliogràfiques
Autors principals: Mizoguchi, Fumitaka, Murakami, Yousuke, Saito, Tetsuya, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978447/
https://ncbi.nlm.nih.gov/pubmed/24004633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4282
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