miR-31 controls osteoclast formation and bone resorption by targeting RhoA

INTRODUCTION: Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppr...

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Bibliographische Detailangaben
Hauptverfasser: Mizoguchi, Fumitaka, Murakami, Yousuke, Saito, Tetsuya, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978447/
https://ncbi.nlm.nih.gov/pubmed/24004633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4282
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