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Lack of ADAM10 in endothelial cells affects osteoclasts at the chondro-osseus junction

PURPOSE: Mice lacking ADAM10 in endothelial cells (Adam10ΔEC mice) have shorter femurs, tibiae and humeri than controls, raising questions about how endothelial cells could control long bone growth. METHODS: We performed a histopathological evaluation of the femur and tibia growth plates at differen...

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Autors principals: Zhao, Ren, Wang, Aimin, Hall, Katherine C., Otero, Miguel, Weskamp, Gisela, Zhao, Baohong, Hill, Daniel, Goldring, Mary B., Glomski, Krzysztof, Blobel, Carl P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978382/
https://ncbi.nlm.nih.gov/pubmed/24108673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22492
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