Mice Lacking the Metalloprotease-Disintegrin MDC9 (ADAM9) Have No Evident Major Abnormalities during Development or Adult Life

MDC9 (ADAM9/meltrin γ) is a widely expressed and catalytically active metalloprotease-disintegrin protein that has been implicated in the ectodomain cleavage of heparin-binding epidermal growth factor-like growth factor (HB-EGF) and as an α secretase for the amyloid precursor protein. In this study,...

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Main Authors: Weskamp, Gisela, Cai, Hui, Brodie, Thomas A., Higashyama, Shigeki, Manova, Katia, Ludwig, Thomas, Blobel, Carl P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC134708/
https://ncbi.nlm.nih.gov/pubmed/11839819
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