Essential Role for ADAM19 in Cardiovascular Morphogenesis

Congenital heart disease is the most common form of human birth defects, yet much remains to be learned about its underlying causes. Here we report that mice lacking functional ADAM19 (mnemonic for a disintegrin and metalloprotease 19) exhibit severe defects in cardiac morphogenesis, including a ven...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Zhou, Hong-Ming, Weskamp, Gisela, Chesneau, Valérie, Sahin, Umut, Vortkamp, Andrea, Horiuchi, Keisuke, Chiusaroli, Riccardo, Hahn, Rebecca, Wilkes, David, Fisher, Peter, Baron, Roland, Manova, Katia, Basson, Craig T., Hempstead, Barbara, Blobel, Carl P.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2004
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673146/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.96-104.2004
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