Essential Role for ADAM19 in Cardiovascular Morphogenesis

Congenital heart disease is the most common form of human birth defects, yet much remains to be learned about its underlying causes. Here we report that mice lacking functional ADAM19 (mnemonic for a disintegrin and metalloprotease 19) exhibit severe defects in cardiac morphogenesis, including a ven...

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Main Authors: Zhou, Hong-Ming, Weskamp, Gisela, Chesneau, Valérie, Sahin, Umut, Vortkamp, Andrea, Horiuchi, Keisuke, Chiusaroli, Riccardo, Hahn, Rebecca, Wilkes, David, Fisher, Peter, Baron, Roland, Manova, Katia, Basson, Craig T., Hempstead, Barbara, Blobel, Carl P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC303363/
https://ncbi.nlm.nih.gov/pubmed/14673146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.96-104.2004
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