Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-κB

Recently, a broader role of inhibitor of apoptosis (IAP) proteins besides their antiapoptotic functions has been described. Therefore, we investigated the effect of non-toxic concentrations of the small-molecule Smac mimetic BV6, which antagonizes IAP proteins, on differentiation of cancer stem-like...

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Detalhes bibliográficos
Main Authors: Tchoghandjian, A, Jennewein, C, Eckhardt, I, Momma, S, Figarella-Branger, D, Fulda, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978303/
https://ncbi.nlm.nih.gov/pubmed/24488095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.200
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