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Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells

As inhibitor of apoptosis (IAP) proteins can regulate additional signaling pathways beyond apoptosis, we investigated the effect of the second mitochondrial activator of caspases (Smac) mimetic BV6, which antagonizes IAP proteins, on non-apoptotic functions in glioblastoma (GBM). Here, we identify n...

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Detalhes bibliográficos
Main Authors: Tchoghandjian, A, Jennewein, C, Eckhardt, I, Rajalingam, K, Fulda, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615728/
https://ncbi.nlm.nih.gov/pubmed/23538445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.70
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