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Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner()

Second mitochondria-derived activator of caspase (Smac) mimetics are considered as promising anticancer therapeutics that are currently under investigation in early clinical trials. They induce apoptosis by antagonizing inhibitor of apoptosis proteins, which are frequently overexpressed in cancer. W...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Lindemann, Carina, Marschall, Viola, Weigert, Andreas, Klingebiel, Thomas, Fulda, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719005/
https://ncbi.nlm.nih.gov/pubmed/26152356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.05.002
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