Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner()

Second mitochondria-derived activator of caspase (Smac) mimetics are considered as promising anticancer therapeutics that are currently under investigation in early clinical trials. They induce apoptosis by antagonizing inhibitor of apoptosis proteins, which are frequently overexpressed in cancer. W...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Lindemann, Carina, Marschall, Viola, Weigert, Andreas, Klingebiel, Thomas, Fulda, Simone
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719005/
https://ncbi.nlm.nih.gov/pubmed/26152356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.05.002
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