Inhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152

Glioblastomas (GBMs) are the most aggressive primary brain tumors in adult and remain a therapeutic challenge. Targeting key apoptosis regulators with the ultimate aim to restore apoptosis in tumor cells could be an interesting therapeutic strategy. The inhibitors of apoptosis proteins (IAPs) are re...

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Vydáno v:Cell Death Dis
Hlavní autoři: Tchoghandjian, A, Soubéran, A, Tabouret, E, Colin, C, Denicolaï, E, Jiguet-Jiglaire, C, El-Battari, A, Villard, C, Baeza-Kallee, N, Figarella-Branger, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108315/
https://ncbi.nlm.nih.gov/pubmed/27490930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.214
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