Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment

Active Caspase-6 is abundant in the neuropil threads, neuritic plaques and neurofibrillary tangles of Alzheimer disease brains. However, its contribution to the pathophysiology of Alzheimer disease is unclear. Here, we show that higher levels of Caspase-6 activity in the CA1 region of aged human hip...

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Main Authors: LeBlanc, A C, Ramcharitar, J, Afonso, V, Hamel, E, Bennett, D A, Pakavathkumar, P, Albrecht, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978300/
https://ncbi.nlm.nih.gov/pubmed/24413155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.194
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