Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment

Active Caspase-6 is abundant in the neuropil threads, neuritic plaques and neurofibrillary tangles of Alzheimer disease brains. However, its contribution to the pathophysiology of Alzheimer disease is unclear. Here, we show that higher levels of Caspase-6 activity in the CA1 region of aged human hip...

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Detalhes bibliográficos
Main Authors: LeBlanc, A C, Ramcharitar, J, Afonso, V, Hamel, E, Bennett, D A, Pakavathkumar, P, Albrecht, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978300/
https://ncbi.nlm.nih.gov/pubmed/24413155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.194
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