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A new role for an old player: Steroid receptor RNA Activator (SRA) represses hormone inducible genes

In breast cancer cells the Steroid Receptor RNA Activator (SRA) acts as scaffold of a complex containing HP1γ, LSD1, HDAC1/2 and CoREST, which contributes to repression of key hormone-inducible genes that must be kept silent in the absence of hormone.

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Podrobná bibliografie
Hlavní autoři: Beato, Miguel, Vicent, Guillermo P
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977916/
https://ncbi.nlm.nih.gov/pubmed/23863201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.25777
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