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Steroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation
How genes are repressed by steroid hormones remains a matter of debate, and several indirect mechanisms have been proposed. We found that the ligand-activated progesterone receptor recruits to the promoter of downregulated genes a repressor complex composed of HP1γ, the lysine demethylase LSD1, hist...
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| 出版年: | Transcription |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279715/ https://ncbi.nlm.nih.gov/pubmed/27700223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1242456 |
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