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A new role for an old player: Steroid receptor RNA Activator (SRA) represses hormone inducible genes
In breast cancer cells the Steroid Receptor RNA Activator (SRA) acts as scaffold of a complex containing HP1γ, LSD1, HDAC1/2 and CoREST, which contributes to repression of key hormone-inducible genes that must be kept silent in the absence of hormone.
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977916/ https://ncbi.nlm.nih.gov/pubmed/23863201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.25777 |
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