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Gentian violet induces wtp53 transactivation in cancer cells

Recent studies suggest that gentian violet (GV) may have anticancer activity by inhibiting for instance NADPH oxidases (Nox genes) whose overexpression is linked to tumor progression. Nox1 overexpression has been shown to inhibit transcriptional activity of the oncosuppressor p53, impairing tumor ce...

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Bibliographic Details
Main Authors: GARUFI, ALESSIA, D’ORAZI, VALERIO, ARBISER, JACK L., D’ORAZI, GABRIELLA
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977805/
https://ncbi.nlm.nih.gov/pubmed/24535435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2304
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