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RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling

R-spondins (RSPOs) and their receptor leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) play pleiotropic roles in normal and cancer development as well as the survival of adult stem cells through potentiation of Wnt signaling. Current evidence indicates that RSPO–LGR4 functions to e...

詳細記述

保存先:
書誌詳細
主要な著者: Carmon, Kendra S., Gong, Xing, Yi, Jing, Thomas, Anthony, Liu, Qingyun
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977305/
https://ncbi.nlm.nih.gov/pubmed/24639526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323106111
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