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RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling

R-spondins (RSPOs) and their receptor leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) play pleiotropic roles in normal and cancer development as well as the survival of adult stem cells through potentiation of Wnt signaling. Current evidence indicates that RSPO–LGR4 functions to e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carmon, Kendra S., Gong, Xing, Yi, Jing, Thomas, Anthony, Liu, Qingyun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977305/
https://ncbi.nlm.nih.gov/pubmed/24639526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323106111
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