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RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling
R-spondins (RSPOs) and their receptor leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) play pleiotropic roles in normal and cancer development as well as the survival of adult stem cells through potentiation of Wnt signaling. Current evidence indicates that RSPO–LGR4 functions to e...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977305/ https://ncbi.nlm.nih.gov/pubmed/24639526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323106111 |
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