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LGR5 Interacts and Cointernalizes with Wnt Receptors To Modulate Wnt/β-Catenin Signaling

LGR5, a seven-transmembrane domain receptor of the rhodopsin family, is a Wnt target gene and a bona fide marker of adult stem cells in the gastrointestinal tract and hair follicle bulge. Recently, we and others demonstrated that LGR5 and its homologues function as receptors of the R-spondin family...

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Detalhes bibliográficos
Main Authors: Carmon, Kendra S., Lin, Qiushi, Gong, Xing, Thomas, Anthony, Liu, Qingyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372227/
https://ncbi.nlm.nih.gov/pubmed/22473993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00272-12
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