Dual regulation of G proteins and the G-protein–activated K(+) channels by lithium

Lithium (Li(+)) is widely used to treat bipolar disorder (BPD). Cellular targets of Li(+), such as glycogen synthase kinase 3β (GSK3β) and G proteins, have long been implicated in BPD etiology; however, recent genetic studies link BPD to other proteins, particularly ion channels. Li(+) affects neuro...

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Autores principales: Farhy Tselnicker, Isabella, Tsemakhovich, Vladimir, Rishal, Ida, Kahanovitch, Uri, Dessauer, Carmen W., Dascal, Nathan
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977261/
https://ncbi.nlm.nih.gov/pubmed/24639496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316425111
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