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Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma
Much controversy surrounds the cell-of-origin of mutant K-Ras (K-RasG12D)–induced lung adenocarcinoma. To shed light on this issue, we have used technology that enables us to conditionally target K-RasG12D expression in Surfactant Protein C (SPC)(+) alveolar type 2 cells and in Clara cell antigen 10...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977239/ https://ncbi.nlm.nih.gov/pubmed/24586047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319963111 |
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