Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis

Tumor heterogeneity can create a unique symbiotic tumor microenvironment. Earlier, we showed that clonal evolution in mouse small cell lung cancer (SCLC) can result in subclones that, upon cografting, endow the neuroendocrine tumor cells with metastatic potential. We now show that paracrine signalin...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Kwon, Min-chul, Proost, Natalie, Song, Ji-Ying, Sutherland, Kate D., Zevenhoven, John, Berns, Anton
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2015
Onderwerpen:
Research Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536306/
https://ncbi.nlm.nih.gov/pubmed/26215568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.262998.115
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