Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis

Tumor heterogeneity can create a unique symbiotic tumor microenvironment. Earlier, we showed that clonal evolution in mouse small cell lung cancer (SCLC) can result in subclones that, upon cografting, endow the neuroendocrine tumor cells with metastatic potential. We now show that paracrine signalin...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Kwon, Min-chul, Proost, Natalie, Song, Ji-Ying, Sutherland, Kate D., Zevenhoven, John, Berns, Anton
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2015
Teme:
Research Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536306/
https://ncbi.nlm.nih.gov/pubmed/26215568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.262998.115
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