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SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

Lung squamous cell carcinoma (LSCC) is a devastating malignancy with no effective treatments, due to its complex genomic profile. Therefore, preclinical models mimicking its salient features are urgently needed. Here we describe mouse models bearing various combinations of genetic lesions predominan...

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Bibliografiske detaljer
Udgivet i:Cancer Cell
Main Authors: Ferone, Giustina, Song, Ji-Ying, Sutherland, Kate D., Bhaskaran, Rajith, Monkhorst, Kim, Lambooij, Jan-Paul, Proost, Natalie, Gargiulo, Gaetano, Berns, Anton
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065004/
https://ncbi.nlm.nih.gov/pubmed/27728803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.001
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