SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

Lung squamous cell carcinoma (LSCC) is a devastating malignancy with no effective treatments, due to its complex genomic profile. Therefore, preclinical models mimicking its salient features are urgently needed. Here we describe mouse models bearing various combinations of genetic lesions predominan...

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Publicado en:Cancer Cell
Autores principales: Ferone, Giustina, Song, Ji-Ying, Sutherland, Kate D., Bhaskaran, Rajith, Monkhorst, Kim, Lambooij, Jan-Paul, Proost, Natalie, Gargiulo, Gaetano, Berns, Anton
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065004/
https://ncbi.nlm.nih.gov/pubmed/27728803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.001
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