SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

Lung squamous cell carcinoma (LSCC) is a devastating malignancy with no effective treatments, due to its complex genomic profile. Therefore, preclinical models mimicking its salient features are urgently needed. Here we describe mouse models bearing various combinations of genetic lesions predominan...

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Библиографические подробности
Опубликовано в: :Cancer Cell
Главные авторы: Ferone, Giustina, Song, Ji-Ying, Sutherland, Kate D., Bhaskaran, Rajith, Monkhorst, Kim, Lambooij, Jan-Paul, Proost, Natalie, Gargiulo, Gaetano, Berns, Anton
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065004/
https://ncbi.nlm.nih.gov/pubmed/27728803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.001
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