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Temporal Dissection of K-ras(G12D) Mutant In Vitro and In Vivo Using a Regulatable K-ras(G12D) Mouse Allele
Animal models which allow the temporal regulation of gene activities are valuable for dissecting gene function in tumorigenesis. Here we have constructed a conditional inducible estrogen receptor-K-ras(G12D) (ER-K-ras(G12D)) knock-in mice allele that allows us to temporally switch on or off the acti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350485/ https://ncbi.nlm.nih.gov/pubmed/22606359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037308 |
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