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Age-related Brain Expression and Regulation of the Chemokine CCL4/MIP-1β in APP/PS1 Double Transgenic Mice

The detrimental effect of activation of the chemokine CCL4/MIP-1β on neuronal integrity in patients with HIV-associated dementia has directed attention to the potential role of CCL4 expression and regulation in Alzheimer disease (AD). Here, we show that CCL4 mRNA and protein are overexpressed in the...

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Detalhes bibliográficos
Main Authors: Zhu, Min, Allard, Joanne S., Zhang, Yongqing, Perez, Evelyn, Spangler, Edward L., Becker, Kevin G., Rapp, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977177/
https://ncbi.nlm.nih.gov/pubmed/24607962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000060
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