טוען...
Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures
Germline TP53 mutations predispose to multiple cancers defining Li-Fraumeni/Li-Fraumeni-like syndrome (LFS/LFL), a disease with large individual disparities in cancer profiles and age of onset. G-quadruplexes (G4s) are secondary structural motifs occurring in guanine tracks, with regulatory effects...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977145/ https://ncbi.nlm.nih.gov/pubmed/24336192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt381 |
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