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The importance of Raf dimerization in cell signaling
The Raf family of protein kinases are key signaling intermediates, acting as a central link between the membrane-bound Ras GTPases and the downstream kinases MEK and ERK. Raf kinase regulation is well-known for its complexity but only recently has it been realized that many of the mechanisms involve...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976976/ https://ncbi.nlm.nih.gov/pubmed/23985533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.26117 |
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